溶血型大腸桿菌

peppen

通風不良的問題~產房保溫使用密閉式的保溫方式~保溫箱這類的...有沒有影響??

蘇少儀

前文是想以趣談方式說明這種疾病不會是大流行的型態呈現...................撰文仍然考慮有欠週到
老師問起來，要更認真回答................

溶血性大腸桿菌是Escherichia coli 0157 食品安全造成人類的嚴重的腸炎，不是豬的(如下文)
造成豬水腫病的大腸桿菌具有溶血性，但大腸桿菌在哺乳及離乳豬的原發性疾病仍是腸內毒素(Enterotoxins)造成的下痢(即腸道感染)為主．
豬腸道內分離的病原性大腸桿菌就分為溶血性(佔絕大多數)及非溶血性的．會吃料且飼料中的酸化程度夠的話，大腸桿菌應不為患．
就"溶性性大腸桿菌症"而言，由田間豬隻的臨床症狀而言，現已正式發表的文獻，應該是離乳後大腸桿菌症．
另外，時下如果高比率豬隻發生離乳後大腸桿菌症，氣溫，女豬佔分娩母豬群的比例升高及併發於病毒性病原的感染等因素才是需要考量的．

謝謝林老師指正...................說話有影響力的人更應謹言慎行.................

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Deaths from renal failure after outbreaks of acute gastroenteritis in Scotland in 1996, which were traced back to poor hygiene in butchers’ shops, focused attention on Escherichia coli 0157 and its links with the haemolytic uraemic syndrome. Although in the Scottish outbreak deaths occurred mainly in elderly people, haemolytic uraemic syndrome associated with diarrhoea generally affects children and is the commonest cause of acute renal failure in children in Europe and North America.
Haemolytic uraemic syndrome is the most important complication of infection by verocytotoxin producing E coli—usually of the serotype 0157:H7, though other serotypes are also implicated. It is characterised by the sudden onset of haemolytic anaemia with fragmentation of red blood cells, thrombocytopenia, and acute renal failure after a prodromal illness of acute gastroenteritis often with bloody diarrhoea. The gastrointestinal disease may be severe, with haemorrhagic colitis, and the central nervous system, pancreas, lungs and heart may also be affected. Fortunately more than 95% of people affected with this condition do recover from the acute illness, and recurrence is unusual. The longer term prognosis remains unclear; follow up studies have shown 15-40% of survivors with renal sequelae.3,4
The annual incidence of infection with verotoxin E coli ranges from 1-30 cases per 100000 in industrialised countries and is highest in young children under 5 years and during the warmer months. During outbreaks of infection about 8% of patients develop haemolytic uraemic syndrome. The infective dose of E coli 0157:H7 is 50-100 organisms and the incubation period to onset of diarrhoea 1-8 days. Younger children may continue to excrete the bacteria for more than three weeks after the infection, but asymptomatic prolonged carriage of E coli 0157 is unusual.
The natural reservoir of verotoxin producing E coli is the intestinal tracts of domestic animals, especially cattle, and bovine foods such as ground beefburgers and unpasteurised milk are major sources for human infection. Other foods, including cider and vegetables such as lettuce and radish sprouts, are becoming increasingly recognised as sources. E coli 0157:H7 has been recovered from many retail foods including fresh seafood, lamb, chicken, pork, venison, and veal. Person to person transmission of E coli 0157, facilitated by the low infectious dose, is a source of human infection.
The initial cases of an outbreak and many sporadic cases of E coli 0157:H7 disease may go unrecognised because routine stool cultures do not differentiate these E coli from normal enteric flora. Not all laboratories in the United Kingdom screen for the pathogen. Also, although the disease eventually manifests as bloody diarrhoea, it usually begins with non-bloody diarrhoea and this may be difficult to differentiate from the acute viral gastroenteritis commonly seen in children.
Children at particular risk of developing haemolytic uraemic syndrome after infection with verotoxin producing E coli are younger, have a high presenting white blood cell count, and have bloody rather than non-bloody diarrhoea.5 The use of antimotility or antidiarrhoeal agents is an additional risk factor, and the toxin type of the infecting strain may also be important.6 The prevention of secondary and epidemic spread would be greatly facilitated by looking for E coli 0157 in faecal samples. Clearly not all children with diarrhoea should have stool cultures, but when stools are sent to the laboratory from children, particularly those with risk factors, they should be tested for E coli 0157:H7.
Once haemolytic uraemic syndrome caused by verotoxin producing E coli has developed there is no specific treatment yet available. Prompt diagnosis and good supportive care to maintain hydration, electrolyte balance, and nutrition are crucial, as is the management of the critical complications of cerebral oedema, severe ischaemic colitis, myocardial dysfunction, and diabetes mellitus. Studies are in progress to identify novel treatments that may halt the development of haemolytic uraemic syndrome in E coli infection, such as the use of a synthetic oligosaccharide receptor for the verotoxin.7 Understanding of the pathogenetic mechanisms and of the pivotal role of verocytotoxin at a cellular level is increasing,8 and this will clearly be valuable in developing treatments. Of greatest benefit is preventing primary and secondary infection with verotoxin producing E coli, and this should be the focus of public health policy.
Preventing E coli 0157:H7 disease is difficult as the organisms colonise the intestines of healthy cattle and other food animals. They are also resistant to acidic conditions, dehydration, and high salt concentrations. Public health control thus requires vigilance at all stages of the food chain. Safe food handling and proper cooking will destroy the organism, and the risk of foodborne disease can be reduced by limiting possible cross contamination. Irradiation dramatically reduces the risk of E coli 0157:H7 infection by killing these organisms, and this approach has been recommended as safe and effective by consumer groups and an independent scientific panel.9 In the United States the Food and Drug Administration approved irradiation of red meat in December 1997. In future the use of a toxoid vaccine,10 which has potential given the established central role of verocytotoxin in the pathogenesis of haemolytic uraemic syndrome, may help to eradicate the disease altogether. For now, sound public health measures remain paramount.(BMJ. 1999 March 13; 318(7185): 684–685.)

[ 本帖最後由 蘇少儀 於 2009-1-14 19:23 編輯 ]

peppen

金水細D注落企ㄟ金水??
那是甚麼東東?

singing1978

豬水腫病是仔豬的一種急性致死性疾病，主要發生斷奶前後，以斷奶後的仔豬發病率較高，而且同窩生長健壯的仔豬易發。本病發病突然，病程短，死亡快。發病率低於30％，但病死率卻高達80％∼90％。發病原因如下：
file:///C:/DOCUME~1/singing/LOCALS~1/Temp/msohtml1/01/clip_image001.gif
溶血性大腸桿菌：本病關鍵因素，腸道病菌產生之毒素引起毒血症，毒素積聚到一定程度，就引起仔豬發病，導致死亡。
file:///C:/DOCUME~1/singing/LOCALS~1/Temp/msohtml1/01/clip_image001.gif
仔豬不健全的消化系統：離乳仔豬因消化功能不健全，消化酶活性低，胃酸分泌少，易導致消化不良、腸道內菌群失去平衡，因而致病性大腸桿菌大量繁殖產生毒素，除造成下痢外，更會引發水腫病。

所以若要採用非抗生素的方式降低水腫病狀況，可使用能殺菌的酸化劑，配合具腸毒素吸附效果的吸附劑進行處理

[ 本帖最後由 singing1978 於 2009-1-14 16:01 編輯 ]

蘇少儀

原帖由 peppen 於 14/1/2009 10:22 發表
金水細D注落企ㄟ金水??
那是甚麼東東?

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早上，心情比較好，開個玩笑
形容藥品價格，但是價格貴的藥品要進一步分析，不能僅看產品單價.................有點引喻失當

[ 本帖最後由 蘇少儀 於 2009-1-14 19:20 編輯 ]

104s

其實
只要讓豬  回歸到 最原始的食物就好
管理者  佩帶著寶刀利劍  山珍海味都用盡了  貪圖豪華的飼效   我真的曾經看過   飽育舍的小豬  可以比寧大豬的身材{就是講小豬  有沒有  要露司  後腿肉有沒有?  寬不寬  ..就好像馬上把小豬放大  就是將來的大豬   如果猴猴的8分飽  那麼就是小時候猴猴  長大也會猴猴的   潮流是講時效性   要快 要少  又要高價位}     大豬棟的溫控  比我自己產房還溫暖的   講真的  看完了  我才發現  自己真的是井底之蛙:028

對了
講那麼多  沒講到重點吼    就是小豬不要太營養  不要太飽食  豬不要太薄皮  不好刁    毛衣與櫬衫  毛衣一定比較好  刁粗料的  但價格也不見的  有多差

[ 本帖最後由 104s 於 2009-1-14 19:37 編輯 ]

團長

[女豬佔分娩母豬群]
原意是否為[新女豬佔分娩母豬群]

蘇少儀

原帖由 團長 於 14/1/2009 19:43 發表
[女豬佔分娩母豬群]
原意是否為[新女豬佔分娩母豬群]

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因為是談哺乳或離乳仔豬
所以女豬指的是第一胎(初次)分娩的母豬(例如每批10頭分娩母豬中第一胎母豬的比例)

[ 本帖最後由 蘇少儀 於 2009-1-14 20:43 編輯 ]

peppen

發現的時候都變成肉條了~連針劑的錢都省了....:016

peppen

你說的是"水D"卡歹飼嗎??..........